Discovery of Selective Small-Molecule CD80 Inhibitors
نویسندگان
چکیده
منابع مشابه
Discovery of selective small-molecule CD80 inhibitors.
Protein-protein interactions are widely found in biological systems controlling diverse cellular events. Because these interactions are implicated in many diseases such as autoimmunity and cancer, regulation of protein-protein interactions provides ideal targets for drug intervention. The CD80-CD28 costimulatory pathway plays a critical role in regulation of the immune response and thus constit...
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ژورنال
عنوان ژورنال: Journal of Biomolecular Screening
سال: 2007
ISSN: 1087-0571,1552-454X
DOI: 10.1177/1087057107300464